The following are the stages of life cycle of Plasmodium. Arrange the stages in the proper order.

A. The parasites reproduce asexually in RBCs, bursting the cells.

B. The parasites reproduce asexually in liver cells, bursting the cells and releasing into blood.

C. Gametocytes develop in RBCs.

D. Sporozoites reach the liver through the blood.

E. Female mosquito injects sporozoites into humans during bite.

Choose the correct answer from the options given below:

Question

The following are the stages of life cycle of Plasmodium. Arrange the stages in the proper order.

A. The parasites reproduce asexually in RBCs, bursting the cells.

B. The parasites reproduce asexually in liver cells, bursting the cells and releasing into blood.

C. Gametocytes develop in RBCs.

D. Sporozoites reach the liver through the blood.

E. Female mosquito injects sporozoites into humans during bite.

Choose the correct answer from the options given below:

Accepted Answer

A. 1. Recall the Plasmodium life cycle sequence in the human host, which begins with the mosquito bite and ends with the formation of gametocytes.

2. Understand the starting point — infection begins when a **female Anopheles mosquito injects sporozoites** into a human during a bite (step E).

3. Trace the path of the sporozoites — after entering the body, the sporozoites travel through the blood and **reach the liver** (step D).

4. Recognize the asexual multiplication in the liver — inside liver cells, the parasites multiply asexually, and when these cells burst, the parasites are **released into the blood** (step B).

5. Recognize the asexual multiplication in RBCs — the released parasites then infect RBCs, multiply asexually, and burst the RBCs, causing the characteristic fever cycles (step A).

6. Recognize the formation of the sexual stage — some parasites inside RBCs transform into **gametocytes**, the sexual stage, ready to be picked up by another mosquito (step C).

7. Hence, the correct order is **E, D, B, A, C (Option A)**.